JayCel™-103

JayCel™-103 is a specialized low-moisture pharmaceutical-grade Microcrystalline Cellulose engineered for moisture-sensitive formulations, superior compactibility, and dependable processing performance. With controlled particle distribution and reduced loss on drying, it delivers excellent formulation stability, efficient blending characteristics, and reliable compression performance across pharmaceutical, nutraceutical, and advanced tablet manufacturing applications.

Technical Details

JayCel™-103 Microcrystalline Cellulose

JayCel™-103 is a premium pharmaceutical-grade Microcrystalline Cellulose developed for low-moisture formulation needs, excellent compressibility, and consistent particle performance. With controlled loss on drying and balanced particle size distribution, it supports stable processing, reliable tablet formation, and dependable functionality across pharmaceutical and nutraceutical applications.

AppearanceWhite Powder

pH Range5.0 – 7.5

Assay Dried97.0 – 102.0%

Bulk Density0.26 – 0.34 g/ml

Physical Characteristics

DescriptionWhite or almost white, fine or granular crystalline powder.Reference: USP

SolubilityInsoluble in water, dilute acids, and most organic solvents including anhydrous ethanol, acetone, and toluene.Reference: Ph. Eur / BP

Sodium Hydroxide SolubilityPractically insoluble in sodium hydroxide solution.Reference: Ph. Eur / BP

Special Solubility TestDissolve 50 mg in 10 ml ammonical solution of copper tetramine R. It dissolves completely, leaving no residue.Reference: Ph. Eur / BP

pHpH of the supernatant solution should be between 5.0 to 7.5.Reference: USP/NF, JP, Ph.Eur, BP

ConductivityConductivity of the supernatant solution should not exceed 75 µS/cm.Reference: USP/NF, JP, Ph.Eur, BP

Loss on DryingNot more than 3.0% w/w.Reference: USP/NF, JP, Ph.Eur, BP

Bulk Density0.26 to 0.34 g/ml.Reference: In-house

Degree of Brightness85%.Reference: In-house

Angle of ReposeMaximum 42°.Reference: In-house

Identification & Compliance

Infrared AbsorptionRecord the infrared absorption spectrum and compare with the reference spectrum.Reference: JP / USP

Color ReactionThe substance takes on a violet-blue color.Reference: USP, Ph.Eur, BP, JP

Degree of PolymerizationNot more than 350.Reference: USP, Ph.Eur, BP, JP

Chemical Purity Profile

Residue on Ignition / Sulphated AshNot more than 0.1%.Reference: USP/NF, JP, Ph.Eur, BP

Starch & DextrinsComplies with IP limit test.Reference: IP

Organic ImpuritiesHave to correspond as per IP.Reference: IP

Water Soluble SubstancesNot more than 0.25% w/w.Reference: USP/NF, JP, Ph.Eur, BP

Ether Soluble SubstancesNot more than 0.05% w/w.Reference: USP/NF, JP, Ph.Eur, BP

Heavy MetalsNot more than 10 ppm.Reference: USP/NF, JP, Ph.Eur, BP

ArsenicNot more than 2 ppm.Reference: IP

Assay Dried97.0 – 102.0%.Reference: In-house

Particle Size Distribution

D10

≤ 30 µ

Reference: In-house

D50

40 – 60 µ

Reference: In-house

D90

≥ 80 µ

Reference: In-house

Sieve Analysis

60 Mesh Retention≤ 1.0%.Reference: In-house

200 Mesh Retention≤ 30.0%.Reference: In-house

Microbial Safety Standards

Total Aerobic Microbial Count
Maximum 1000 cfu/g.Reference: USP/NF, JP, Ph.Eur, BP

Total Combined Molds & Yeasts
Maximum 100 cfu/g.Reference: USP/NF, JP, Ph.Eur, BP

Staphylococcus aureus
Absent.Reference: USP/NF, JP, Ph.Eur, BP

Pseudomonas aeruginosa
Absent.Reference: USP/NF, JP, Ph.Eur, BP

Escherichia coli
Absent.Reference: USP/NF, JP, Ph.Eur, BP

Salmonella species
Absent.Reference: USP/NF, JP, Ph.Eur, BP

Storage & Solvent Compliance

Storage RecommendationPreserve in tight containers.Reference: Specification Requirement

Organic Volatile ImpuritiesRaw materials, manufacturing process, and product do not contain solvents listed in Organic Volatile Impurities.Reference: USP <467>

Residual SolventsRaw materials, manufacturing process, and product do not contain listed residual solvents.Reference: Ph.Eur <5.4>

Technical Note: JayCel™-103 specifications are designed to support low-moisture performance, controlled quality, and reliable compliance across pharmaceutical and industrial formulation requirements.