JayCel™-102

JayCel™-102 is a premium pharmaceutical-grade Microcrystalline Cellulose developed for enhanced flowability, superior binding performance, and improved formulation uniformity. With a slightly larger particle size distribution and optimized bulk density, it delivers excellent processing efficiency and consistent tablet compression performance across pharmaceutical, nutraceutical, and high-speed manufacturing applications.

Technical Details

JayCel™-102 Microcrystalline Cellulose

AppearanceWhite Powder

pH Range5.0 – 7.5

Assay Dried97.0 – 102.0%

Bulk Density0.27 – 0.34 g/ml

Physical Characteristics

DescriptionWhite or almost white, fine or granular crystalline powder.Reference: USP

SolubilityInsoluble in water, dilute acids, and most organic solvents including anhydrous ethanol, acetone, and toluene.Reference: Ph. Eur / BP

Sodium Hydroxide SolubilityPractically insoluble in sodium hydroxide solution.Reference: Ph. Eur / BP

Special Solubility TestDissolve 50 mg in 10 ml ammonical solution of copper tetramine R. It dissolves completely, leaving no residue.Reference: Ph. Eur / BP

pHpH of the supernatant solution should be between 5.0 to 7.5.Reference: USP/NF, JP, Ph.Eur, BP

ConductivityConductivity of the supernatant solution should not exceed 75 µS/cm.Reference: USP/NF, JP, Ph.Eur, BP

Loss on DryingNot more than 7.0% w/w.Reference: USP/NF, JP, Ph.Eur, BP

Bulk Density0.27 to 0.34 g/ml.Reference: In-house

Degree of Brightness85%.Reference: In-house

Angle of ReposeMaximum 42°.Reference: In-house

Identification & Compliance

Infrared AbsorptionRecord the infrared absorption spectrum and compare with the reference spectrum.Reference: JP / USP

Color ReactionThe substance takes on a violet-blue color.Reference: USP, Ph.Eur, BP, JP

Degree of PolymerizationNot more than 350.Reference: USP, Ph.Eur, BP, JP

Chemical Purity Profile

Residue on Ignition / Sulphated AshNot more than 0.1%.Reference: USP/NF, JP, Ph.Eur, BP

Starch & DextrinsComplies with IP limit test.Reference: IP

Organic ImpuritiesHave to correspond as per IP.Reference: IP

Water Soluble SubstancesNot more than 0.25% w/w.Reference: USP/NF, JP, Ph.Eur, BP

Ether Soluble SubstancesNot more than 0.05% w/w.Reference: USP/NF, JP, Ph.Eur, BP

Heavy MetalsNot more than 10 ppm.Reference: USP/NF, JP, Ph.Eur, BP

ArsenicNot more than 2 ppm.Reference: IP

Assay Dried97.0 – 102.0%.Reference: In-house

Particle Size Distribution

D10

10 – 55 µ

Reference: In-house

D50

80 – 140 µ

Reference: In-house

D90

170 – 283 µ

Reference: In-house

Sieve Analysis

60 Mesh Retention< 8.0%.Reference: In-house

200 Mesh Retention≥ 45.0%.Reference: In-house

Microbial Safety Standards

Total Aerobic Microbial Count
Maximum 1000 cfu/g.Reference: USP/NF, JP, Ph.Eur, BP

Total Combined Molds & Yeasts
Maximum 100 cfu/g.Reference: USP/NF, JP, Ph.Eur, BP

Staphylococcus aureus
Absent.Reference: USP/NF, JP, Ph.Eur, BP

Pseudomonas aeruginosa
Absent.Reference: USP/NF, JP, Ph.Eur, BP

Escherichia coli
Absent.Reference: USP/NF, JP, Ph.Eur, BP

Salmonella species
Absent.Reference: USP/NF, JP, Ph.Eur, BP

Storage & Solvent Compliance

Storage RecommendationPreserve in tight containers.Reference: Specification Requirement

Organic Volatile ImpuritiesRaw materials, manufacturing process, and product do not contain solvents listed in Organic Volatile Impurities.Reference: USP <467>

Residual SolventsRaw materials, manufacturing process, and product do not contain listed residual solvents.Reference: Ph.Eur <5.4>

Technical Note: JayCel™-102 specifications are designed to support enhanced flowability, controlled quality, and reliable compliance across pharmaceutical and industrial formulation requirements.